BIOSTRUCT aims to advance the surface patterning of biomedical implants using Resorbink’s amino acid phosphoramide (APA) technology. The project will focus on formulating novel biodegradable and biocompatible photo-resins tailored for high-resolution surface structuring. Employing nanoimprint lithography (NIL), biodegradable micro- and nanostructured surfaces will be fabricated, designed to enhance biocompatibility, promote tissue integration, and reduce infection risks and lowering the probability of implant failure. Unlike conventional NIL materials, APA-based formulations offer intrinsic biocompatibility and biodegradability, making them ideally suited for regenerative medical applications.

During the project we will develop biodegradable, biomimetic NIL compatible resins and demonstrate the applicability of NIL to planar, porous, and anatomically curved implant surfaces, with subperiosteal implants serving as a representative use case for improved micropatterned implant design. This work will pave the way for the scalable manufacturing of personalized implants with tailored surface properties, contributing to innovation in regenerative medicine and advanced biomaterials. 

 Resorbink is a biomaterials company developing next generation photocurable, biodegradable polymers for advanced medical applications. The company’s materials are based on amino acids and phosphorus, designed to support healing and safely break down in the body. 

Designed for applications such as tissue engineering and medical 3D printing, including DLP and inkjet technologies, Resorbink’s materials combine high resolution processability with true bioresorbability. This allows the fabrication of functional structures that support healing and safely degrade into natural, bioactive components. 

Fotocredits: Resorbink, Profactor